Green Cap Heparin Tube

Heparin is a mucopolysaccharide containing sulfate groups and carries a strong negative charge. Its anticoagulant mechanism is to enhance the activity of antithrombin III, enhancing its ability to inactivate serine protease, thereby preventing thrombin formation and inhibiting platelet aggregation to achieve anticoagulant effects.

heparin tubes on the market are further divided into sodium heparin and lithium heparin, with specific considerations for choosing between the two:

Lithium heparin: Considered the ideal choice because lithium ions do not interfere with most biochemical tests (such as blood glucose, enzymes, ionized calcium, etc.) and do not introduce additional sodium ions. This is why heparin lithium separation tubes are the "golden partner" for emergency biochemistry.

Sodium heparin: Relatively inexpensive, but not suitable for sodium ion detection because the pre-stored sodium salt in the tube can severely overestimate the patient's blood sodium level.

Precise anticoagulant dosage: The standard dosage of heparin is typically 10.0~12.5 IU/ml blood. This dose range has been clinically validated and ensures effective anticoagulation within 6 hours, without significantly affecting white blood cell count or morphology due to overdose.

Emergency and routine biochemical testing: This is the most common use of heparin tubes. Due to its fast anticoagulation rate and non-dilution of samples, it is widely used in emergency biochemistry, general biochemistry, and hemorheology assays.

Trace element and blood gas analysis: Heparin has minimal effect on most ions and is suitable for trace element detection. At the same time, it is also commonly used for erythrocyte fragility tests, blood gas analysis, hematocrit tests, and more.

1. Fastest anticoagulation speed: Heparin binds directly to AT-III to inactivate thrombin, skipping intermediate steps such as chelating calcium ions. Compared to sodium citrate (blue-capped tube), which requires calcium ions to be fully cheated, heparin completes anticoagulation at the moment of blood collection, making it the fastest anticoagulant option in the emergency green channel.
2. High plasma separation efficiency: The heparin lithium tube contains inert separation gel, which forms a stable barrier between blood cells and plasma after centrifugation, allowing direct machine testing without manual plasma separation, avoiding fibrin filament clogging and greatly improving the processing efficiency of automated production lines.
3. High degree of standardization: Plasma samples collected from heparin lithium tubes are highly compatible with the reagent systems of mainstream biochemical analyzers, resulting in stable and reliable results. Our products comply with international quality certifications such as CE and ISO13485, ensuring traceability of results.